Research

• Cardiovascular Pharmacology & Vascular Biology -
  
• Endothelium-dependent responses.
• Regulation of vascular function by male and female hormones and the signal transduction pathways.
• Vascular effect of phytoestrogens and compounds derived from Chinese herbs; pharmacology of Chinese medicine.
• Low-density lipoprotein modification, endothelial function and endothelium-derived vasoactive factors.
  

• Toxicology and Drug Metabolism -
  
• Pharmacological modulation of drug-induced tissue injury.
• Antioxidant defence mechanisms in oxidative stress.
• Pro-inflammatory mediators in disease.
• DNA damage by anti-tumour agents and subsequent repair mechanisms.

• Cellular Signalling and Herbal Medicines -
  
• Intracellular signaling pathways, specifically the mitogen-activated and stress-activated pathways in coronary disease.
• Biological actions of green tea.
• Study of the effects of pure compounds found in herbal medicines on the cardiovascular system.
• Antioxidant actions of flavonoids and their involvement in the restoration of normal vascular function in pathological conditions.
• Molecular and biochemical pharmacology of herbal medicine.

• Adipokine-based Translational Pharmacology -
  
• Cardiovascular and metabolic functions of animal models with adipokine dysfunctions.
• Pharmacogenomics, proteomics and metabolomics with an emphasis on obesity-related cardiovascular and metabolic diseases.
• Pre-clinical evaluation for adipokine-based therapeutical development.
  
  
• Drug Delivery -
  
• Respiratory and intranasal drug delivery.
• Development and physicochemical characterisation of novel formulations.
• Functionalise polymer material by surface modification for specific targeting.
• Non-viral delivery of plasmid DNA, small interference RNA (siRNA), oligonucleotides, proteins and peptides.
• Cellular uptake and intracellular trafficking of macromolecules.
• Live cell confocal imaging and in vivo imaging of therapeutic macromolecules.
  
  
• Novel Therapy against Infectious Diseases -
  
• RNA interference therapy against bacteria and viral infections.
• Development of antimicrobial peptide against microorganisms.
  
  
• Nanotechnology -
  
• Pharmaceutical nanotechnology and novel nanoparticles synthesis.
• Nanoparticle drug delivery system.
• Nanotoxicity.
  
  
• Pharmacy Practice -
  
• Medication safetyPaediatric pharmacoepidemiology and paediatric psychopharmacology.
• Paediatric formulations.
• Clinical and pharmacy practice-based research.
• Pharmacoeconomics.
• Management of adverse events in chemotherapyUse of Traditional Chinese Medicine (TCM) in oncology patients.

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